Victoria E. Prince, PhD

My research program at the University of Chicago focuses on vertebrate axial regionalization during development using the zebrafish as a model. My group takes a variety of molecular, cellular and genetic approaches to these studies, and we have made important contributions to a variety of research areas, including the understanding of Hox gene regulation of hindbrain patterning, evolution of duplicated genes and genomes in the vertebrates, and patterning of endoderm-derived tissues. Active areas of research in my lab include continuing studies of hindbrain patterning, with an emphasis on understanding neuronal and neural crest migration.

Princeton University
Princeton, NJ
Postdoc - Developmental Bio
1997

University of London, Guy's Hospital
London
Postdoc - Developmental Neuro
1994

University College, London University
London
PhD - Molecular Biology
1991

Imperial College, London University
London
BS - Biochemistry
1986

Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body.
Rocha M, Kushkowski E, Schnirman R, Booth C, Singh N, Beadell A, Prince VE. Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body. Dev Biol. 2021 Dec; 480:25-38.
PMID: 34389276

Midline morphogenesis of zebrafish foregut endoderm is dependent on Hoxb5b.
Dalgin G, Prince VE. Midline morphogenesis of zebrafish foregut endoderm is dependent on Hoxb5b. Dev Biol. 2021 03; 471:1-9.
PMID: 33290819

From head to tail: regionalization of the neural crest.
Rocha M, Beiriger A, Kushkowski EE, Miyashita T, Singh N, Venkataraman V, Prince VE. From head to tail: regionalization of the neural crest. Development. 2020 10 26; 147(20).
PMID: 33106325

Development and migration of the zebrafish rhombencephalic octavolateral efferent neurons.
Beiriger A, Narayan S, Singh N, Prince V. Development and migration of the zebrafish rhombencephalic octavolateral efferent neurons. J Comp Neurol. 2021 05 01; 529(7):1293-1307.
PMID: 32869305

Rapid image deconvolution and multiview fusion for optical microscopy.
Guo M, Li Y, Su Y, Lambert T, Nogare DD, Moyle MW, Duncan LH, Ikegami R, Santella A, Rey-Suarez I, Green D, Beiriger A, Chen J, Vishwasrao H, Ganesan S, Prince V, Waters JC, Annunziata CM, Hafner M, Mohler WA, Chitnis AB, Upadhyaya A, Usdin TB, Bao Z, Colón-Ramos D, La Riviere P, Liu H, Wu Y, Shroff H. Rapid image deconvolution and multiview fusion for optical microscopy. Nat Biotechnol. 2020 11; 38(11):1337-1346.
PMID: 32601431

Neural crest development: insights from the zebrafish.
Rocha M, Singh N, Ahsan K, Beiriger A, Prince VE. Neural crest development: insights from the zebrafish. Dev Dyn. 2020 01; 249(1):88-111.
PMID: 31591788

Prickle1 is required for EMT and migration of zebrafish cranial neural crest.
Ahsan K, Singh N, Rocha M, Huang C, Prince VE. Prickle1 is required for EMT and migration of zebrafish cranial neural crest. Dev Biol. 2019 04 01; 448(1):16-35.
PMID: 30721665

Zebrafish Pancreas Development and Regeneration: Fishing for Diabetes Therapies.
Prince VE, Anderson RM, Dalgin G. Zebrafish Pancreas Development and Regeneration: Fishing for Diabetes Therapies. Curr Top Dev Biol. 2017; 124:235-276.
PMID: 28335861

Differential levels of Neurod establish zebrafish endocrine pancreas cell fates.
Dalgin G, Prince VE. Differential levels of Neurod establish zebrafish endocrine pancreas cell fates. Dev Biol. 2015 Jun 01; 402(1):81-97.
PMID: 25797153

Rest represses maturation within migrating facial branchiomotor neurons.
Love CE, Prince VE. Rest represses maturation within migrating facial branchiomotor neurons. Dev Biol. 2015 May 15; 401(2):220-35.
PMID: 25769695

View All Publications

Faculty Leadership Award in Program Innovation
University of Chicago
2016 - 2016

Marshal of the University
The University of Chicago
2015 - 2018

Academic Leadership Fellowship
CIC/University of Chicago
2010 - 2011

J &J Neubauer Faculty Development Fellowship in recognition of teaching excellence in the College
University of Chicago
2006 - 2006

The Christianna Smith Lecturer
Mount Holyoke College
2005 - 2005

Faculty of 1000
2005 - 2010

Human Frontiers Science Program Fellowship
Princeton University
1995 - 1997

EMBO Long-Term Fellowship
Princeton University
1994 - 1995

Medical Research Council (UK) Training Fellowship
1992 - 1994